Helping Your Heart and Your Memory

Resveratrol: Its Beneficial Effects

Would you like to make a simple healthful change to benefit your heart? Resveratrol elevates HDL levels, the good cholesterol. Having a high HDL doesn’t mean you are protected against developing heart disease, but those with high HDLs appear to have reduced risk for coronary artery disease. Two human studies have also shown resveratrol can boost insulin activity in Type II diabetics and reduce harmful blood vessel disease leading to diabetic blindness. Another effect is the reduction in fat cell production of inflammatory compounds that contribute to heart disease and tissue damage associated with diabetes.

This natural product, obtainable in most pharmacies and health food stores, stimulates a family of sirtuin proteins in the body that are gene regulators. Metabolic and biological aging processes are affected by sirtuins, especially the protein SIRT1. Researchers at Howard Hughes Medical Institute found SIRT1 plays a roll in decreasing aging and aids learning and memory. Most of us could benefit from that!

Another protein resveratrol stimulates is CREB, which  strengthens connections between neurons. The CREB activity is increased by SIRT1.  There won’t be an SIRT1 pill coming soon, but understanding this relationship shows promise in understanding and reversing degenerative processes causing memory loss. Resveratrol in your diet may help your memory.

Diets rich in resveratrol protect the heart, increase fat burning and reduce weight gain—and in mice, extend lifespan. The compound is found in grapes, grape products, wine, peanuts and some plants. A trade product containing resveratrol called Reversitol comes in both pill and liquid forms. It tastes like grape juice and is easily tolerated as a food supplement.

Betty Kuffel, MD

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